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Hypofractionated proton therapy in early stage NSCLC
(Bush et al: Int J Rad Onc Bio Phy 86:964,
2013)
N= 107
Dose escalation: 52Gy, 60 Gy and 70 Gy in 10 fx
4 years: OS: 18%, 32% and 51%
T1 LC: 96%
T2 LC and OS: Trend in improvement with 70 Gy level
No Grade 2 RP noted
No difference between central vs. peripheral lesions
O
S