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Hypofractionated proton therapy in early stage NSCLC

(Bush et al: Int J Rad Onc Bio Phy 86:964,

2013)

N= 107

Dose escalation: 52Gy, 60 Gy and 70 Gy in 10 fx

4 years: OS: 18%, 32% and 51%

T1 LC: 96%

T2 LC and OS: Trend in improvement with 70 Gy level

No Grade 2 RP noted

No difference between central vs. peripheral lesions

O

S