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Historical niche of proton therapy indications
Pediatric
Adult
•
Skull base, paraspinal and sacral
chordoma and (chondro)sarcoma
•
Glioma
•
Imaging 1950-1970s
–
Indirect target imaging
•
Bone, air
•
Contrast
–
Radio-opaque markers-spacers
–
Target edges
•
Calculation
•
Informed guess
•
Immobile targets
–
Nearby bone
–
Superficial
–
No moving organs in path