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Margins ? ! ?

But margins for ………….

uncertainties in seed placement ?

- x/y direction – no problems

- z direction – corrections during implantation

change of volume ?

- only temporary problem

- edema resolves within the first ½ life of seeds

change of position ?

- eventual use of stabilization needles

- continuous on-line verification of position

So:

forget about margins for PTV definition PTV = CTV