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mpMR imaging after EBRT
- EBRT causes overall changes in signal intensity and structure of the prostate
- The irradiated prostate appears smaller as a result of gland atrophy and
differentiation of the zones is made difficult by effacement of the prostatic tissue
- The entire prostate appears more hypointense on T2w imaging inducing
difficulties in the:
- differentiation between central and peripheral zone
- distinction between benign and tumour tissues
- Sensitivity for T2w alone is varies between 36% and 75% and specificity ranged
fro m65% to 81% (Sala et al.)
So: limited value of T2w in this setting.