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Multicentric phase II

Lille, Nancy & Nice

Patients

N = 56

Sex n (%)

M

43 ( 75.4)

F

14 ( 24.6)

Age,

60 (42 – 80)

0

20

40

60

80

Percent

15 20 25 30 35 40 45 50 55 60 65 70

Duration Cetux (days)

Dose and duration

N=56

Duration (days)

Median (range)

28 (15-70)

Total dose cycle 1 (mg/m²)

Median (range)

400 (307-426)

0

20

40

60

80

Percent

500

1000

1500

2000

2500

Total Dose Cetuximab (mgm2)

77 % response at 3 months