SBRT2015

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Very limited gain in TCP for doses >100Gy BED
Grills JTO 2010; Ohiri IJROBP 2012
0 20 40 60 80 100 120 140 160 180 200
BED10Perscription dose PTV (Gy)
0.0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1.0
Local control
Guckenberger Radiother Oncol 2013
= 3 x 18Gy
Dose effect modelling – individual patient data
Matthias Guckenberger - DEGRO 2015 25
n=505 n=395
29.08.2015