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Matthias Guckenberger - DEGRO 2015
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Tolerance of OARs
Extrapolation from experiences in conventionally fractionated RT
Lack of validation
Organ at risk
1 fx
(RTOG 0915)
3 fx
(RTOG 0618 / 1021)
5 fx
(RTOG 0815)
8 fx
Haasbeck et al. 2011)
Trachea and large
bronchus
D
max
20.2 Gy
D
max
30 Gy
D
max
105% *
18 Gy < 5cc **
D
max
44 Gy
---
Heart
D
max
22 Gy
16 Gy < 15cc
D
max
30 Gy
---
D
max
105% *
32 Gy < 15cc
---
Esophagus
D
max
15.4 Gy
11.9 Gy < 5cc
D
max
25.2 Gy
17.7 G< 5cc
D
max
105% *
27.5 Gy < 5cc **
D
max
40 Gy
---
Brachial plexus
D
max
17.5 Gy
14 Gy < 3cc
D
max
24 Gy
20.4 Gy < 3cc
D
max
32 Gy
30 Gy < 3cc
D
max
36 Gy
---
Chest wall
D
max
30 Gy
22 Gy < 1cc
---
30 Gy < 30cc
60 Gy < 3 cc
---
30 Gy < 30cc
60 Gy < 3 cc
---
Spinal cord
D
max
14 Gy
10 Gy < 0.35cc
D
max
18 Gy (RTOG 0236) D
max
30 Gy
22.5 Gy <0.25cc
---
Guckenberger Strahlentherapie 2013
29.08.2015