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SABR & pulmonary interstitial changes
•
260 consecutive SABR cases with primary lung cancer
•
Pre-treatment pulmonary interstitial fibrosis (PIF) group (n=18);
non-PIF group (n=242)
•
Grade ≥2 radiation pneumonitis in 9 (
50.0%
) of PIF group
versus 14 (
6.7%
) in non-PIF group
•
3 patients with grade 5 RP were all in PIF group.
CONCLUSION:
On multivariate analysis, the presence of PIF was the only
significant predictive factor of ≥grade 2 pneumonitis
Yoshitake T, Anticancer Res 2015