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Priority areas for research
PATIENT'SELECTION'
◦
If$a$RCT$is$not$feasible$in$medically$operable$ES9NSCLC$patients,$investigate$the$
role$of$SABR$through$CER$using$detailed$prospective$registration$of$comorbidity$
and$toxicity$data$
◦
Establish$the$risks$and$benefits$of$SABR$in$CT9screened$ES9NSCLC$lung$cancer$
patients$
◦
Develop$robust$prediction$models$for$distant$metastasis$risk$in$order$to$guide$
adjuvant$treatment$
◦
Establish$the$safety$and$appropriate$administration$of$adjuvant$systemic$therapy$
◦
Identify$patients$in$whom$SABR$should$not$be$offered,$due$to$high$risk$of$early$
mortality$from$competing$causes$
!
Louie AV, Radioth Oncol 2015