910 / 1138
•
Randomized phase III →
phase II
•
CT (FOLFOX + Avastin) + RFA
vs. CT alone
•
2003-2007: 119 pts.; m-FU:
4.4 yrs.
•
Inclusion: 1-9 CRC liver
mets. (60%>4)
Ruers Ann Oncol 2012; 23:2619
OS: P=0.22
PFS: P=0.03
CLOCC - EORTC 40004