SBRT2015

Margins: Frame-based versus IGRT-

frameless

•

Combs

et al.

(IJROBP 2009), the DKFZ experience comparing

fractionated stereotactic radiotherapy (FSRT) using a relocatable

frame-based mask system and stereotactic radiosurgery (SRS) using

an invasive frame for treatment of Vestibular Schwannoma (N=202):

Comparable local control rates 96% at 5 years

The PTV was defined after a fusion of CT/MR images as the area

of contrast enhancement on T1-weighted MRI images, with the

addition

of a 1-2 mm safety margin, both for FSRT and SRS

•

Meijer

et al.

(IJROBP 2003), the VUMC experience for Vestibular

Schwannoma (N=129):

2 Groups: dentate patients – FSRT, edentated patients SRS

Again,

comparable results

, with small difference in trigeminal

nerve preservation rate in favor of FSRT.

minimum safety margin of 1mm was used in both groups

SBRT 2015 - D. Verellen