980 / 1138
8
SBRT for re-irradiation
Re-irradiation tolerance and recovery
Factors associated with recovery:
•
Initial biological dose in relationship to tolerance dose
•
Initial volume irradiated
•
Time interval between treatment courses
Skin & mucosa
Small intestine
Mesechymal
Bone
Full – partial
Partial
Partial
Partial
Lung
pneumonitis Lung fibrosis
Heart
Bladder
Kidney
Full – partial
No
No
No
No
Normal tissue tolerance