18
SBRT for re-irradiation
Spinal cord tolerance – reirradiation:
Animal studies
26 minipigs, uniform 30Gy in 10 Fx
Reirradiation after 1 year:
−
Inhomogeneous (10-90%) SRS
−
14.9Gy – 25.4Gy
ED
50
of 19.7Gy
Identical SRS tolerance as in the primary
situation
Full recovery of 30Gy in 10 Fx within 1
year
Medin IJROBP 2011
Re-irradiation for spinal metastases