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18

SBRT for re-irradiation

Spinal cord tolerance – reirradiation:

Animal studies

26 minipigs, uniform 30Gy in 10 Fx

Reirradiation after 1 year:

Inhomogeneous (10-90%) SRS

14.9Gy – 25.4Gy

ED

50

of 19.7Gy

Identical SRS tolerance as in the primary

situation

Full recovery of 30Gy in 10 Fx within 1

year

Medin IJROBP 2011

Re-irradiation for spinal metastases