47 / 120
3/9/2017
7
SMPR Key Points
Concentrates
Parameter
Requirement
THC, THCA, CBDA, CBD,
Individually Reported
Requirement
(Additional,
Desirable
Cannabinoids
(Table 1b),
including CBN)
Limit of
Quantitation (LOQ)
(% w/w)
≤ 0.3
≤ 0.3
Analytical Range
(% w/w)
≤ 0.3 – ca. 100
≤ 0.3 – ca. 50
Dried Plant Material
Parameters
Ranges (% w/w)
≤ 0.3 – 1
> 1 ‐ 10 > 10 – ca.
100
Recovery (% w/w)
95 – 105
97 ‐ 103 98 ‐ 102
% RSD
r
≤ 5
≤ 4
≤ 2
% RSD
R
≤ 7
≤ 5
≤ 3
Parameters
Ranges (%)
(Pertains to Cannabinoids in Table 1b)
0.1 – 1
> 1 ‐ 25 > 25 – ca. 50
Recovery (%)
95 – 105
97 ‐ 103
98 ‐ 102
% RSD
r
≤ 5
≤ 4
≤ 2
% RSD
R
≤ 7
≤ 5
≤ 3
Parameter
Requirement
(Pertains to Cannabinoids
in Table 1b)
Limit of Quantitation (LOQ) (%)
≤ 0.1
Analytical Range (%)
0.1 – ca. 50*
*Lower concentrations may be acceptable as applicable for
cannabinoids listed in Table 1B.
Comments Submitted
5 Comments were received for SMPR –dried
materials.
1. The proposed procedures should add (a)
Instrument Detection Limit (IDL), and (b)
Method Detection Limit (MDL)
Action: WG decided to use LOD which is the
equivalent of IDL, which uses blank matrix
samples; LOD uses matrix samples. MDL was
purposefully removed by the WG.