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PracticeUpdate® is a registered

trademark of Elsevier Inc.

2017 Elsevier Inc.

All rights reserved.

ABOUT

For a complete listing of disclosures for each board member and

editorial contributor, please refer to their profile on PracticeUpdate.com

PracticeUpdate

’s mission is to help medical professionals navigate the

vast array of available literature and focus on the most critical information

for their patients and practice.

All journal articles selected for

PracticeUpdate

receive a Take-Home

Message designed to quickly summarize the key findings and explain

the importance of that research within the specialty area. The most

critical articles also receive Expert Commentaries from experts who are

handpicked by the

PracticeUpdate

Editorial Board, providing additional

context on that research for the reader. Expert Opinion pieces give special

highlights to important topics and Conference Coverage captures relevant

takeaways from a vast array of medical meetings throughout the year.

PracticeUpdate Oncology

provides coverage of key research from

leading international conferences, and a collection of top journal articles

and accompanying expert commentaries in a convenient print periodical.

These and more are also available online at PracticeUpdate.com

PracticeUpdate

and

PracticeUpdate Oncology

are commercially

supported by advertising, sponsorship, and educational grants. Individual

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PracticeUpdate

is a commercially-sponsored product, it maintains

the highest level of academic rigour, objectivity, and fair balance

associated with all Elsevier products. No editorial content is influenced

in any way by commercial sponsors or content contributors.

DISCLAIMER

PracticeUpdate Oncology

has been developed for specialist medical

professionals. The ideas and opinions expressed in this publication do

not necessarily reflect those of the Publisher. Elsevier will not assume

responsibility for damages, loss, or claims of any kind arising from or

related to the information contained in this publication, including any claims

related to the products, drugs, or services mentioned herein. Because

of rapid advances in the medical sciences, in particular, independent

verificationofdiagnosesanddrugdosagesshouldbemade.Pleaseconsult

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editorial policies of Elsevier’s PracticeUpdate.com. All content printed in

this publication can be found on PracticeUpdate.com

CONTENT

Abstracts are available when the publisher grants permission from

MEDLINE/PubMed, a database of the US National Library of Medicine.

• NLM data are produced by a US Government agency and include

works of the United States Government that are not protected by US

copyright law but may be protected by non-US copyright law, as well

as abstracts originating from publications that may be protected by

US copyright law.

• NLM assumes no responsibility or liability associated with use

of copyrighted material, including transmitting, reproducing,

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provide legal advice regarding copyright, fair use, or other aspects

of intellectual property rights. Persons contemplating any type of

transmission or reproduction of copyrighted material such as abstracts

are advised to consult legal counsel.

SALES

Fleur Gill

fleur.gill@elsevier.com

Linnea Mitchell-Taverner

l.mitchell@elsevier.com

PRODUCTION

Content was originally published on PracticeUpdate.com

Production of this issue was executed by:

Editorial Manager

A

nne Neilson

anne.neilson@elsevier.com

Editorial Project Manager

Carolyn Ng

• Designer

Jana Sokolovskaja

Cover: Lung cancer cells – 3D illustration

PracticeUpdate Oncology

is published by Elsevier Australia

ISSN 2207-869X (Print) ISSN 2207-8703 (Online)

ABN 70 001 002 357

475 Victoria Avenue Chatswood NSW 2067 Australia

Locked Bag 7500 Chatswood DC NSW 2067

EMON101701

PRACTICE UPDATE ONCOLOGY BOARD

PracticeUpdate is guided by a world-renowned Editorial and Advisory Board that represents

community practitioners and academic specialists with cross-disciplinary expertise.

Editor-in-Chief

Lee Schwartzberg

MD, FACP

Executive Director of the West Cancer Center, a multispecialty oncology practice affiliated with the

University of Tennessee; Professor of Medicine and Division Chief of Hematology/Oncology at The

University of Tennessee Health Science Center

Associate Editors

Isabel Cunningham

MD

Adjunct Associate Research Scientist,

Division of Hematology Oncology,

Columbia University College of Physicians

and Surgeons

Axel Grothey

MD

Consultant, Division of Medical Oncology,

Department of Oncology, Mayo Clinic;

Professor of Oncology, Clinical and

Translational Science, Mayo Graduate

School, Rochester, Minnesota

Advisory Board

Benjamin Anderson

MD, FACS

Professor of Surgery and Global

Health-Medicine, University of

Washington; Director, Breast Health Clinic,

Seattle Cancer Care Alliance, Seattle,

Washington

Kimberly Blackwell

MD

Professor of Medicine and Assistant

Professor in Radiation Oncology, Duke

Department of Medicine, Durham, North

Carolina

Roxana Dronca

MD

Assistant Professor of Oncology, Mayo

Clinic College of Medicine, Rochester,

Minnesota

Wilfried Eberhardt

MD

Associate Director, Regional Outreach

West German Cancer Centre

University Hospital of University of

Duisburg-Essen

Rafael Fonseca

MD

Chair, Department of Internal Medicine;

Mayo Clinic, Phoenix/Scottsdale, Arizona;

Getz Family Professor of Cancer, Mayo

Clinic School of Medicine, Phoenix/

Scottsdale, Arizona

Andre Goy

MD

Chairman and Director, John Theurer

Cancer Center, Chief of Lymphoma, John

Theurer Cancer Center at Hackensack

University Medical Center

Annette Hasenburg

Prof. Dr. med

Director of Obstetrics and Gynecology

Mainz University Medical Center, Mainz,

Germany

David Henry

MD

Clinical Professor of Medicine,

Pennsylvania Hospital

Eric Jonasch

MD

Professor, Department of Genitourinary

Medical Oncology, Division of Cancer

Medicine; Director, VHL Clinical Center,

The University of Texas MD Anderson

Cancer Center, Houston, Texas

Jeffrey Kirshner

MD, FACP

Partner of Hematology Oncology Assoc of

Central New York, East Syracuse; Director

of Research, HOACNY Community Clinical

Oncology Program

Howard Scher

MD

Chief, Genitourinary Oncology Service,

Sidney Kimmel Center for Prostate and

Urologic Cancers, Memorial Sloan-

Kettering Cancer Center

David Straus

MD

Attending Physician, Lymphoma Service,

Department of Medicine, Memorial

Sloan-Kettering Cancer Center, New York,

New York

Roger Stupp

MD

Professor of Neurological Surgery,

Neurology, and Oncology, Northwestern

University Feinberg School of Medicine;

Co-Director, Northwestern Brain Tumor

Institute; Associate Director for Strategic

Initiatives, Robert H. Lurie Comprehensive Cancer Center

of Northwestern University, Chicago Illinois

Editorial Contributors

Brandt Esplin

MD, PhD

Hematology/Oncology Fellow, Mayo

Clinic Graduate School of Medical

Education, Rochester, Minnesota

Jeremy Jones

MD

Fellow, Hematology and Medical

Oncology, Mayo Clinic, Rochester,

Minnesota

Neil Majithia

MD

Fellow in Hematology/Oncology, Mayo

Clinic School of Graduate Medical

Education, Rochester, Minnesota

Jarushka Naidoo

MD

Assistant Professor of Oncology, Sidney

Kimmel Cancer Center, Johns Hopkins,

Baltimore, Maryland

Moshe Ornstein

MD

Hematology/Oncology Fellow, Cleveland

Clinic Taussig Cancer Institute, Cleveland,

Ohio

Erin Schenk

MD, PhD

Hematology/Oncology Fellow, Clinician-

Investigator Training Program, Mayo

School of Graduate Education

Jeffrey Wiisanen

MD

Hematology/Medical Oncology Fellow,

Mayo Clinic School of Graduate Medical

Education, Rochester, Minnesota