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13

EMBRACE II interventions

Increased use of IC/IS technique in BT:

HR CTV >30cm3: utilisation of IC/IS of >70% patients and CTV

HR

>85Gy in

80% of patients (63% in EMBRACE I))

Reduction of vaginal source loading

Systematic utilisation of IMRT

Utilisation of daily IGRT (set-up according to bony structures)

EBRT target concept related to the primary tumour; concepts for

OAR contouring

EBRT dose prescription (45Gy/25fx) and reporting

Adaptation of EBRT nodal elective CTV according to risk of

nodal and systemic recurrence

Systematic application of simultaneous chemotherapy

Reduction of overall treatment time