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Dose

CTV-HR dose ≥85 Gy (D90) delivered in 7 weeks provide 3

year LC rates of

>94% in limited size (20 cc)

>93% in intermediate size (30 cc)

>86% in large size (70 cc)

Doses of 90–95 Gy add 1–4% to local control, depending

on tumour volume.

Increased CTV-HR volume by 10 cc requires additional 5

Gy for equivalent local control.

Tanderup et al., RetroEMBRACE, 2016, RadiothOncol