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PTV pathological lymph nodes
CBCT 1st treatment CBCT 24th treatment PTV (blue)
GTV on 10 CBCT (red)
Anne Ramlov, Radiother Oncol. 2017 Apr;123(1):158-163
Assumption:
 Lymph nodes are in a relatively fixed relation to bony anatomy
 Bony registration aligns pathological lymph node target
Most often pathological lymph nodes shrink during RT