242-243 / 1778
EORTC limitation daily activities due to BS
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
EBRT
NAT
very much
quite a bit
a little
not at all
EORTC need to get to toilet in time BS
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
EBRT
NAT
very much
quite a bit
a little
not at all
EORTC Fecal Leakage
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
EBRT
NAT
very much
quite a bit
a little
not at all
EORTC Diarrea
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
EBRT
NAT
very much
quite a bit
a little
not at all
PORTEC-1: Patient reported bowel symptoms 15-years after 46Gy
Nout et al, JCO 2011
Evidence that OAR do not like dose