352 / 1778
Initial SUV
max
(recurrent N):
11 (4-16); p=0.002
D & V: No significant correlation
More failures when
< 5 cycles of ChT (p<0.001)
Ramlov A, et al. Acta Oncologica 2015
3
3
9
isolated PAN recurrences
(1/9: prophylactic PAN RT)
CTV-N
failure
Conclusions:
•
Current boost practice:
control of involved N
•
SUV
max
→
negative prognostic factor
•
Attention: Chemotherapy & Paraaortic RT
139 patients
209 N+ in 75 pts.
SUV
max
= 5 (2-21)
Boost D (EQD2):
D98=62 (53-69) Gy
PET CT, MRI
21 (15 %) pts.:
N relapse
Nodal Boost
Dose