398 / 1778
Comparison 2
NACT followed by Sx Vs RT
• 5 trials
• N = 872
• Planned cycle interval = 10 - 21 days
• Cumulative cisplatin dose = 100 – 300 mg/m2
• RT similar across trials (EBRT 45-60 Gy & ICRT 25-40 Gy)
• One third pts had stage IB & 1/3
rd
stage II