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Neo - adjuvant Chemotherapy:
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NACT followed by RT Vs RT:
No Benefit
- NACT followed by Sx Vs RT:
Some Benefit but has major limitations
- NACT followed by Sx Vs Sx:
CR better but no survival benefit
- NACT followed by Sx Vs Chemo-RT:
Chemo-radiation STD of Care
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Concomitant Chemotherapy :
STD of Care
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Concomitant followed Adjuvant CT :
Still Investigational
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Palliative CT in recent era :
Bevacizumab some benefit
SUMMARY
Chemotherapy IN Cervical Cancers