478 / 1778
➢
5-year actuarial grade 1-4:
•
Overall EBRT 26% versus NAT 4%
•
Grade 1: EBRT 17% versus NAT 4%
•
Majority gastrointestinal tract
➢
Grade 3-4 after EBRT 3%
➢
4-field box technique less late complications
•
30% treated with parallel opposing fields
➢
GOG#99 extended surgery + EBRT 13% grade 3-4
Creutzberg et al, IJROBP2001;
Keys et al 2004
PORTEC-1: morbidity