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From: Harry VN. Gynecol Oncol 2010

Dynamic Contrast Enhanced (DCE) MRI

• Diffusion-weighted imaging (DWI)

• Blood oxygen level dependent (BOLD) MRI

• Proton spectroscopy

Bolus i.v.

Gd contrast

Tumor

neovascularity

Measuring kinetic profile

Modelling tumour perfusion

Transfer Constant - K

trans

V of extracellular space

Extravascular leakage space

Efflux to plasma - K

ep

DCE MRI

Tumor

extracellular

space

Review:

Lee SI, et al. JNM 2015;56(3).

Harry VN. Gynecol Oncol 2010

New MRI technologies