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Consider N involvement when:

PET positive

Intensity (T2)

Diffusion (DWI)

Irregular border

Lost architecture

Round shape

Inhomogeneous

Short axis ≥ 10 mm Short axis 5-10 mm And:

CT + T2w MRI

CT + DW MRI

CT + PET

CT

?

Co-registration of modalities

Detection

Delineation

Are size criteria (short axis <1cm) reliable?