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Seeds with

131

Cs Radioactive Isotope

131

Cs isotope was suggested for BRT use back in 1960s

(Henschke & Lawrence 1965)

Based on Invention made by Donald C. Lawrence in 1967

Developed by IsoRay, Inc. (Richland, WA, USA)

Received FDA 510(k) clearance in 2003

In 2009 FDA clearance for head & neck, lung and other

sites (Proxcelan™

131

Cs Brachytherapy Seeds)