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GEC-ESTRO target volume concept

Potential

Significant

microscopic

Potential

Significant

microscopic

HR CTV

Macroscopic cancer cell density

>80 Gy

-

>60 Gy

-

45Gy

microscopic

microscopic

Cancer cell density

GTV

(visible/palpable tumor)

IR CTV

IR CTV

LR CTV

LR CTV

Pelvic wall

Pelvic wall

Cervix

Residual macroscopic

disease at BT

Initial macro copic extent of disease

Radiother and Oncol 2005