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The problematic Minimum Target Dose or Minimum

Peripheral Dose:

In spite of the high sensitivity of the minimum dose MTD or minimum

peripheral dose MPD in the planning target volume against delineation

inaccuracies and the used resolution of the calculation grid or number

of sample points, these values are still in the national, European,

American and International Reports and Recommendations.

Due to the extended use of individual plan optimisation (prostate, Gyn,

breast, ...) utilising modern inverse optimisation tools in RTPs, the dose

prescription and distribution becomes

individual

and is now

the best

achievable compromise between PTV-related and OAR-related

objectives.

Thus we learned, that we have to distinguish between the

“aimed” or “intended” prescription dose to the PTV (protocol) and the

individually realised – “planned” prescription dose.