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French Cooperative Study

Grade 3-4 complications (%)

related to Dose Rate

< 60 cGy/h

> 60 cGy/h

Ref. bladder dose

0.8 %

5.3 % p = 0.001

Ref. rectal dose

1.7 %

6.5 %

p = 0.01

Mean rectal dose

2.3 %

8.5 %

p = 0.01

J.C. Horiot,ea 1993