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DCE-MRI

Flow

Microvessels in carcinoma versus benign tissue: ratio 2.0

Probably due to angiogenesis

(Bigler 1993)

Resolution: high

Measuring time: short (5 min)

ROI high Flow

Degree of vascularization corresponds with

• aggressive behavior

• risk of metastasis

Treshold e.g.Flow > 20 ml/100g

By courtesy of van Vulpen