Modern Bt Techniques - Florence 2016

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Local recurrences after BCS + RT

BOOST versus NO BOOST

Randomis

e

d

Trials

no boost boost

H.R

.

:

• Lyon

5 y

4.5 %

3.6 % (10 Gy) 0.8

n = 1024

p = 0.044

• French M.C.

5 y

6.8 % 3.6 % (16Gy) 0.53

n = 664

p = 0.13

• EORTC 10801a 5 y

6.8 % 3.4% (15Gy) 0.59

n = 5569

p = 0.0001

•

EORTC 10801b 7y 19%(10 Gy) 9% ( 25Gy)