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Initially : skin – balloon spacing > 5mm is recommended

( Our prediction was : spacing should be at least 15 mm)

2004

: Keish et al 34 % teles at 3 year spacing should

be > 6mm

2005

: Chao et al recommend >7 mm

2006:

Jerusz et al recommend > 7mm

2006

: Niehoff > 5mm : 16 % in boost and 36.5% in APBI

2007

: Belcacémy > 17mm is needed to avoid any TA