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Low-Objective
General Form of a
Dose Objective Function
Inverse Optimisation and Planning
( )
[
]
[
]
( )
1
i
L
i
j
N
p
i
j
i
L
i
D d
d D
f
i
<
∀
−
=
∑
x
x
The Norm Factor
p
D
L
= D
V
for V
100%
High-Objective
D
H
= D
V
for V
0%
1
j i
N
=
( )
[
]
[
]
( )
1
1
i
H
i
j
N
j
p i
H
i
j
i
i
D d
D d
N
f
i
>
∀
−
=
∑
=
x
x
p
= 0 : Volume Objective Function
1 : Linear
2 : Variance based Objective Function