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Patient Selection:

-

HEART:

mediastinal disease extending below the origin of coronaries.

-

BREAST:

young females where proton therapy can reduce breast dose and subsequent risk of secondary

breast cancer.

-

Heavily pretreated patients

who are at higher risk of radiation related toxicities to the heart or lung

When using proton therapy,

the treating physician

should:

-Demonstrate a

benefit

for the patient, due to the increased costs and difficulty in delivering the treatment

compared with photons.

-Understand that lymphoma proton planning is complex, due to the management of

uncertainties

, and

evolving with utilization of PBS, in-room volumetric imaging, and robustness optimization

-Utilize

deep inspiration breath hold

when warranted to further minimize dose to the OARs, understanding

the increased complexity of using DIBH with proton therapy compared with photon therapy