1036 / 1631
Primary extranodal lymphomas,
treatment decision
•
Histopathological type
•
Anatomic extent of disease
•
Specific extranodal involvement
•
Should ideally be based on randomized trials, but:
–
Even fewer exist than for nodal lymphomas
–
Nearly all studies with reasonable follow-up were carried out in the pre-Rituximab era
(important for B-cell lymphomas)
•
Generally based on retrospective series or Phase II studies
•
For rarer extranodal presentations no large patient materials exist, extrapolation
from most ’similar’ cases