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Careful ophthalmologic examination
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Adequate tissue sampling
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Complete history and physical examination
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Routine laboratory studies, serum protein
electrophoresis, serum LDH, β2-microglobulin
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Chest x-ray
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CT of chest, abdomen, and pelvis
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CT-PET
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Bone marrow biopsy (controversial)
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Orbital CT and MRI with contrast enhancement
Diagnosis and staging