Slide 1

PCNSL: epidemiology

• 3.1% of all primary CNS tumors

• Incidence: 0.46/100,000 person years (US)

• ~1000-1500 cases per year (US)

• Median age at diagnosis = 60

• Gender: men: women - 1:1

• Rise in incidence

• Pathology: mostly DLBCL

Central Brain Tumor Registry of the United States (CBTRUS), 1998-2002