1597 / 1631
Total Body Irradiation (TBI)
•
High dose (typically 12 Gy) for convenitonal myeloablative
conditioning for:
–
Allogeneic transplantation:
•
Tumour cell kill
•
Immunosuppression
•
Eradication of cell populations with genetic defects
–
Autologous transplantation:
•
Tumour cell kill
•
Low dose (typically 2-4 Gy) for reduced intenstity conditioning
(RIC) for:
–
Allogeneic transplantation:
•
Immunosuppression