![Show Menu](styles/mobile-menu.png)
![Page Background](./../common/page-substrates/page1607.jpg)
Long-term toxicity
•
Cataract (30-40 %)
•
Gonadal failure
•
Thyroid and kidney dysfunction
•
Decreased bone mineral density
•
Veno-occlusive disease
•
Metabolic syndrome
•
Second cancer
•
Cardiovaxcular disease
•
In children multiple endocrine disorders