1615 / 1631
RT in CNS leukemia (cont)
•
Interval of 2 weeks between i.t. MTX or Ara-C
and CNS-directed RT recommended
•
Choice of cranio-spinal vs. cranial RT depends on
expected long-term outcome
•
High suspicion of therapy-related neurotoxicity in
heavily pre-treated pts. presenting with CNS-
related symptoms