189 / 1631
Trend in cumulative incidence* of lung cancer
by period of
treatment and sex in 5 year HL survivors (n=3,905) and the general population
*estimated in the presence of death as a competing risk
Subdistribution HR are adjusted for age and follow-up<20 years
0.0
5.0
10.0
15.0
20.0
25.0
0 5 10 15 20 25 30 35 40 45
Follow-up time in years
1965-1976
1977-1988
1989-2000
sHR 0.39 (95%CI 0.22-0.69)
1990-2000 versus 1965-1979
♂
0.0
5.0
10.0
15.0
20.0
25.0
Cumulative incidence of lung SMN in females (%)
0 5 10 15 20 25 30 35 40 45
Follow-up time in years
1965-1976
1977-1988
1989-2000
sHR 1.76 (95%CI 0.88-3.51)
1990-2000 versus 1965-1979
♀
Cu ulative incidence of lung SMN (%)
Schaapveld et al , NEJM 2015