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Optimisation: cardiac constraints
o
Mean heart dose is the most used parameter (D
mean
< 5 Gy;
5-15 Gy: acceptable; > 15 Gy: omitting RT or plan
modification), with whole heart evaluated as a single
structure
o
Other dosimetric parameters (V
5
, V
10
, V
30
) are highly
correlated with mean dose
o
Very few data on toxicity according to specific contraints to
different cardiac sub-units
o
Different cardiac structures definition