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Outline of talk

• Early stage –

Is Radiotherapy still standard ?

• Advanced stage

– Low volume asymptomatic –

Is watch and wait still standard ?

– High volume or symptomatic :

standards of care in Immuno-chemotherapy ?

• Relapsed / refractory disease –

How do we predict patients who may

require different treatment approaches ?

• Radioimmunotherapy –

Is there still an opportunity ?

• Targeted Therapies –

Is there life with and after PI3K inhibitors ?