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Effect of R maintenance on Progression Free

Survival (PRIMA at 10 years)

Salles et al, ASH 2017; Abstract #486

PRIMA 10 YEARS

mg_pfskm_yr_I MaintenancePhase, SummaryOf Investigator-AssessedProgression-FreeSurvival, Kaplan-Meier Plots (MITT)

Protocol(s): MO18264(B18264F)

AnalysisPopulation: MITT (N=1018)

Snapshot Date: 26JUN2017 Cutoff Date: 31DEC2016

P<.0001

HR=0.61 (95%CI) 0.52-0.73

10-year PFS

estimates

51%

35%