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RELEVANCE: OVERALL SURVIVAL (IMMATURE; ITT)

1.0

0.9

0.8

0.7

0.6

0.5

0.4

0.3

0.2

0.1

0.0

OS Probability

R

2

R-chemo

0 6 12 18 24 30 36 42 48 54

Months from Randomization

60 66

513 499 491 486 479 459 312 194 105 24 0

2

R

2

Number of Patients at Risk

R-chemo

517 496 487 481 470 453 298 193 115 32

0

R

Data cut-off31May2017.

Fowleret al. RELEVANCE: Phase III Randomized Study of LenalidomidePlus Rituximab (R

2

) Versus ChemotherapyPlus Rituximab,Followedby RituximabMaintenance,in PatientsWith Previously Untreated

FollicularLymphoma. Oral presentation at:American Society of ClinicalOncology meeting.2018; Jun 1-5; Chicago,IL. Abstract 7500.

2

(n = 513)

R-chemo

(n= 517)

Events, n (%)

38 (7)

31 (6)

3-year OS (95% CI)

HR (95% CI)

94% (91%-96%) 94% (91%-96%)

1.16 (0.72-1.86)