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Years

0

2

4

6

8

10

12

14

16

18

20

0.00

0.25

0.50

0.75

1.00

INCIDENCE OF tMDS/tAML

21 patients (17%) have developed tMDS/tAML at median of

5 years (range 0.7-14 years) post HDT

9 patients (10%) in second remission