80 / 1631
•
Historically, radiation therapy (RT) fields/doses were selected
empirically, based largely on experience
•
Physicians relied on clinical intuition to select field sizes/doses.
They understood that these empiric guidelines were imprecise
and did not fully reflect the underlying anatomy, physiology, and
dosimetry
•
For most cases, modern treatments will redistribute, not
eliminate, the dose to normal tissue. The fundamental problem of
treatment planning is how to balance exposure of one organ
against that of another
QUANTEC: Use of NTCP models in the clinic