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P=0.012

18

15

45

40

0

10

20

30

40

50

OR

CR

P=0.008

% Patients

Response at EOT

(IRC)*

33

20

70

58

0

20

40

60

80

BOR

CR

% Patients

Best Overall Response (INV)

*Primary

endpoint

Note: EOT IRC and INV assessments were highly concordant (>90%)

BOR, best overall response; CR, complete response; INV, investigator; IRC, independent review committee; EOT, end of treatment

DLBCL: Significantly Higher PET-CR with Pola-BR

Pola-BR

BR

91