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Who benefits from RT in Agg NHL
•
Early stage disease
•
Advanced stage disease:
Consolidation RT improves outcome after RCHOP:
•
Sites of initial
bulky
disease
•
Extranodal
sites
•
Skeletal
sites
•
(Contralateral testis)
•
Patients who have CMR
may
still benefit from consolidation RT:
•
Retrospective evidence
•
Prospective evidence awaited
•
Selected patients with
persistent PET +vity
can be cured with RT without transplant
•
Salvage:
Radiotherapy has a role in:
•
Peri-transplant:
consolidation or part of debulking
•
Salvage in transplant
ineligible
pts