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Sequenced near neighbors
Whole genome SNP phylogeny of
Francisella
by the Swedish Defense Research Agency (FOI)
SMPR Key Points
•
In silico
screening required
–
Purpose: Predict specificity and inclusivity
across all sequenced
Francisella
strains
–
Approach: Use
Basic Alignment Search Tool
(BLAST) to predict hybridization events
between signatures components (e.g., oligo
primers/probes/amplicons) and available
Francisella
genomic sequences in GenBank
–
Include results of
in silico
analyses in method/
assay performance evaluation reports